Resorbable Molybdenum Implants for Patient Individual Craniomaxillofacial Therapy (MOLY-IMPACT)

Focus topic:	Life Science Technologies
Type of funding:	Project funding programmes
Programme:	CZS Transfer
Funded institution:	Hochschule Offenburg

The project investigates the use of the metal molybdenum as a bone replacement material, for example in the jaw area. A 3D printed model is being developed for this purpose. The biomimetic inner structure is designed to encourage cells to settle and bones to grow.

Goals

To date, bone loss is a disease that is difficult to treat. Existing approaches to restoring bone substance have limited potential for regenerating bone and are therefore only established to a limited extent clinically.

For bony defects in the skull area, individually moldable and highly porous resorbable replacement materials are needed. The metal molybdenum has these properties. It has a high specific strength and rigidity. In addition, it has biocompatible properties without critical tissue reactions. Therefore, research is to be conducted into the realization of implants made of molybdenum.

The biocompatibility is to be increased by 3D printed models with a biomimetic internal structure, since cells of the patient can settle directly. The bone grows into it and the metal dissolves.

The aim is to create the relevant basis for patient-specific, dissolving molybdenum bone replacement implants for transfer into practice. This should improve the treatment of bone loss in the skull.